The implementation of the treatment with tyrosine kinase inhibitors (TKIs) in patients with chronic myelocyte leukemia has significantly influenced the prognosis of the disease. TKI...
Next generation sequencing and its application in clinical genetics
MUDr. Mária Geryková Bujalková, PhD., RNDr. Regina Lohajová Behulová, PhD., RNDr. Renáta Lukačková, RNDr. Gabriel Minárik, PhD., RNDr. Tomáš Szemes, PhD.
The revolutionary method of next generation sequencing (NGS) is based on parallel sequencing analysis of a large number of DNA fragments. The chemical principle of...