The homogeneously staining regions in patients with leukaemia (case reports)
Andrea Blahová, Alexandra Oravcová, Kristína Lengyelová, Alena Žákovičová, Kristína Horváthová, Lucia Žideková, Renata Lukačková
Introduction: The homogeneously staining regions (hsr) just as the dmin represent cytogenetically visible signs of gene amplification. They contain copies of an amplified DNA segment....
Introduction: Acute myeloid leukemia (AML) is a phenotypically and genetically heterogenous clonal disease of blood-forming progenitor cells which causes rapid and uncontrolled proliferation of pathological...
Keywords: AML, cytogenetics, FISH, KMT2 gene, molecular analysis, translocation
Cytogenetic and molecular changes in myelodysplastic syndromes
RNDr. Renáta Lukačková, Mgr. Jakub Petrík, Mgr. Kristína Juríková
Myelodysplastic syndromes (MDS) consist of hematologic diseases which differ in clinical features and also in cytogenetic presentation. They are characterized with abnormal development of at...