The term extracellular vesicles refers to a heterogeneous group of membrane structures released from the cell surface into the extracellular space. This group includes, for...
Accurate prognostic stratification of patients with prostatic adenocarcinoma is substantial for effective therapeutic management. Therefore identification of reliable biomarkers of prostate cancer aggressiveness is still...
Immunodetection techniques are established standards for the identification and quantification of proteins in samples in clinical diagnostics. However, they have limitations, such as the detection...
The goal of the work was to study the effects of pre-analytic factors such as freezing, delayed and prolonged fixation on the immunohistochemical expression of...
Dana Schmidt, Dipl. Ing., Hans Ikenberg, Priv. Doz. Dr. med., Ilona Zeiser, Dr. med., Kristin Eichelkraut, M. Eng., Martina Schmitz, Dr. rer. nat., Matthias Dürst, Prof. Dr.
Aim: An essential event in early carcinogenesis is the hypermethylation of so-called CpG islands, which are predominantly located in promoter/5’ regions of genes in the...