Tumour genesis is accompanied by the activation of antitumour immunity, which has the potential to influence the biological behaviour of the tumour. The present study...

The discovery of antibiotics by Alexander Fleming and the introduction of vaccination are undoubtedly among the most remarkable medical milestones in modern human history. In...

The importance of copy number variants (CNVs) in reference to human health is rising continuously. They are linked to various types of disorders, syndromes and...

Mitochondria play an essential role in the energy metabolism of cells and thus affect essential cellular functions possibly associated with cancer development. Mitochondrial DNA (mtDNA)...

Endometrial adenocarcinoma, often referred as the endometrial cancer, is the most common kind of uterine cancer. It´s incidence is rising in last decades and each...

Depresia každoročne prispieva k celosvetovej záťaži chorôb. Počas krízy COVID-19 sa výskyt porúch nálad či dokonca depresie výrazne zvýšil. Napriek pribúdajúcim informáciám presné základné mechanizmy...

Neonatal meningitis is a life-threatening disease with high mortality rate and possible neurological sequelae with neonatal meningitis E. coli strains (NMEC) being of the primary...

Diabetes mellitus, with its complications, is one of the serious chronic diseases with an increasing prevalence in the population. Common complications of poorly compensated diabetes...

Lynch syndrome (LS), or hereditary non-polyposis colorectal cancer (HNPCC), is an autosomal dominant disease in which mutations occur in genes for MMR proteins responsible for...