ISSN 2454-0021
Genetics
Imunology
Kybernetika
Microbiology
Molecular biology
Pathology
Antiphospholipid antibodies bind to the phospholipids or complex protein-phospholipid. The occurrence of those antibodies can lead to the creation of thrombosis or pregnancy disorders that...
Development of complex chromosome rearrangements in a patient with ALL
RNDr. Andrea Blahová, Alexandra Oravcová, Kristína Lengyelová, RNDr. Renáta Lukačková, Kristína Juríková, Lucia Žideková, Ľubica Majerová, Renata Lukačková, Lenka Cicmanová-Palčová
In the report, we describe an interesting case of 63-year old man with diagnosis of acute lymphoblastic leukaemia. We examined karyotype with cytogenetic methods and...
Application of NGS (next generation sequencing) in routine diagnostics
Lucia Žideková, Ľubica Majerová, Michaela Patáková-Zrubcová, Antónia Hatalová
Next generation sequencing (NGS) also known as massive parallel sequencing is able to detect a large amount of data in a single assay. More than...
Presently, methods based on DNA sequencing are frequently used in clinical microbiology laboratory. Single locus sequencing is a traditional method used for bacterial identification and...
By the using of whole exome and whole genome analyses in the field of genomic medicine, an amount of data generated is increasing widening thus...
Genomic data become more available and affordable because of the advancements in sequencing technologies. Analysis and interpretation of these data, especially genomic variants, is essential...
Primary pancreatic liposarcoma – the case report and literature review
Kristína Mikuš-Kuracinová, Helena Gavurová, Monika Sekerešová
Adenocarcinoma of pancreas presents 85% of all pancreatic tumors, and only 1% of all pancreatic tumors are soft tissue tumors. Liposarcoma is the most common...
Malignant melanoma is a tumour with marked heterogeneity of tumour cells, determining its aggressive behaviour. .Accumulation of mutations, however, leads to the formation of neoantigens,...
HELLP syndrome is a pregnancy-related disease associated with a severe form of preeclampsia; the term HELLP is an abbreviation used to describe a clinical condition...