Whole-genome sequencing methods for CNV detection
Zuzana Klinovská, Marcel Kucharik, Jaroslav Budiš, Tomáš Szemes
The importance of copy number variants (CNVs) in reference to human health is rising continuously. They are linked to various types of disorders, syndromes and...
Extracellular mitochondrial DNA as a non-invasive biomarker of cancer
Silvia Bokorová, Katarína Suroviaková, Ondrej Pös, Werner Krampl, Mgr. Jakub Styk, Tomáš Szemes
Mitochondria play an essential role in the energy metabolism of cells and thus affect essential cellular functions possibly associated with cancer development. Mitochondrial DNA (mtDNA)...
Whole Genome Sequencing as a Tool for Characterization of Neonatal Meningitis Escherichia coli
Michal Andrezál, Lukáš Pazderka, Tomáš Szemes, Hana Drahovská
Neonatal meningitis is a life-threatening disease with high mortality rate and possible neurological sequelae with neonatal meningitis E. coli strains (NMEC) being of the primary...
Lengths of circulating DNA fragments as a promising predictor of cancer stage
Marek Štrba, Jaroslav Budiš, Werner Krampl, Tomáš Sládeček, Ondrej Pös, Mária Lucká, Tomáš Szemes
Bioinformatics has become one of the key scientific disciplines during the 21st century. The aim of this work was to utilize state-of-the-art tools and help...
